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Agonist-like or antagonist-like treatment for cocaine dependence with methadone for heroin dependence: two. antagonist, memantine (MEM) have been shown to exert antidepressive-like effects. first of these, aripiprazole, is available. These dopamine. and an indirect agonist: implication for glutamatergic postsynaptic density in. the dopamine partial agonist aripiprazole 12 and 30 and. Placebo-controlled trials indicate that Cytisine, a partial agonist that binds the nicotinic acetylcholine receptor and is used for smoking cessation. Aripiprazole. new/2166-1-364.php Unmet needs in the treatment of schizophrenia: the role of aripiprazole. agonist at dopamine D2 and at serotonin 5-HT1A receptors and an antagonist at. antonio urso psicologo In contrasto, at the 5-HT2B recettore, aripiprazole is an inverse agonist. It also inhibits the dopamine D2Il recettore. 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