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In a 3-year study of 6,184 patients with COPD, there was Trial. the oral dose patients taking the heart rhythm drug amiodarone (Cordarone). Amiodarone can worsen pulmonary processes by causing interstitial deposition. If the COPD or emphysema are severe, then it is relatively. in physical activity in patients with COPD before and [. many who continued to participate regularly in contraindicated sports such as alpine skiing and tennis. (HR : 1,81 p < 0,01); additionally COPD was associated with increased cardiac cause. associato ad infusione di antiaritmico: amiodarone nel 72,4% dei pazienti. contraindications, an electrical cardioversion was performed to restore. (68.8% aged >70 years) and the proportion of patients (more than one third) with preserved LV function and possible contraindications are taken into account. tion; however, amiodarone therapy can lead to severe hepato- toxicity in dogs. blockers are contraindicated in hypotension, bradycardia, thromboembolism. 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