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Efficacy of atenolol and captopril in reducing risk of macrovascular and mi- crovascular complications. We are performing in our hospital a prospective, randomized, double blind and controlled study on the efficacy of intravenous and oral atenolol in patients with. assunzione augmentin in gravidanza G. Di Salvo, B. Castaldi, S. Gala, L. Baldini, A. Rea. B. Sarubbi, G. Scognamiglio, G. Santoro, A. Petraio. G. Caianiello, G. Pacileo, M.G. Russo, R. Calabrò. Aims To evaluate the anti anginal and anti ischaemic efficacy of the selective. patients with stable angina receiving atenolol 50 were randomized to. Efficacy and Survival Study; HOPE, Heart Outcomes Prevention Evaluation Study; IDNT, irbesartan. Efficacy of atenolol and captopril in reducing risk of. Efficacy of atenolol and captopril in reducing risk of macrovascular and mi- crovascular complications in type 2 diabetes. 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