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Amoxicillin is a penicillin antibiotic used to treat bacterial infections. if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties. kidney problems, phenylketonuria, gonorrhea, or infectious mononucleosis (mono) new/8328-1-11188.php Amoxicillin is a penicillin antibiotic used to treat bacterial infections. if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties. kidney problems, phenylketonuria, gonorrhea, or infectious mononucleosis (mono) Acute infectious mononucleosis presenting with dacryoadenitis and tonsillitis. Acta Ophthalmol Scand. Ampicillin rash in children. Relationship to penicillin. 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