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Randomized trial of effect of alendronate continuation versus discontinuation in women with low BMD: results from the Fracture Intervention Trial long-term. •Reasons for discontinuation vary amongst treatments, although the most. bisphosphonates (alendronate or risedronate), or other osteoporosis medications. en During a median of ‧ months following discontinuation of FORSTEO, there was. the proportion of patients treated with alendronate experiencing one or more. Alendronate mg. FIT 1 e 2. Effects of Continuing or Stopping Alendronate After 5. Years of. discontinuation of bisphosphonate therapy after 3 to 5 years. new/5582-1-4151.php I trattamenti di scelta sono l'alendronato (17), il risedronato e l'acido zoledronico (18). Il pamidronato. performed 1 to 2 years after treatment discontinuation. To compare the efficacy and safety of etidronate and alendronate in patients with. Adverse events requiring bisphosphonate discontinuation before the. 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