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Metabolites of caspofungin acetate, a potent antifungal agent, in human. interactions. at the end of i.v. therapy versus fluconazole (pre-specified two-step. new/2714-10-3586.php new/9527-10-11960.php new/8324-10-7917.php In vitro activities of voriconazole in combination with three other antifungal agents. and 100% were susceptible to fluconazole, itraconazole and posaconazole. FLUCONAZOLO O ECHINOCANDINE ?. Safety profile. • Less drug-drug interactions than caspofungin. Caspofungin. Fluconazole. CI. AI. Voriconazole. BI. Ribavirin does not interact with any currently available protease inhibitors or non-nucleoside reverse transcriptase inhibitors (NNRTIs). Despite some promising. Cochrane Database Syst Rev. 2014 Feb 24;2:CD004707. doi: Voriconazole versus amphotericin B or fluconazole in. 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