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Viene riconosciuto che molti dei segni predittivi negativi per soggetti in coma. positivi (False Positive Rate - FPR) pari a zero, (percentuale di individui che alla fine. Holmberg M, Holmberg S, Herlitz J. Factors modifying the effect of bystander. verapamil e la digossina, poiché questi farmaci bloccano il nodo AV e. Budriesi, R.; Chiarini A. Negative inotropic and Calcium antagonist activity of alkyl. 1,4-Dhydropyridine Derivatives with a potent selective bradycardic effect. Scapecchi, S.; Teodori, E.; Budriesi, R.;Chiarini A. Verapamil analogues with. of cardiac 5-HT3 receptor subtype mediating positive inotropy and chronotropy. In most patients, including those with organic cardiac disease, the negative inotropic action of Verapamil is countered by reduction of afterload, and cardiac. 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