is cetirizine an antihistamine is cetirizine an antihistamine. cetirizine fexofenadine vs loratadine vs cetirizine. cetirizine cetirizine safety in pregnancy cetirizine. Clarinex is an antihistamine. Synonyms: Desloratine. Do NOT use Clarinex if: • you are allergic to any ingredient in Clarinex or to loratadine. if you are pregnant, planning to become pregnant, or are breast-feeding • if you are taking any. None of the antihistamines are officially definitely fine for use in pregnancy. Don't take loratadine, one study linked it to hypospadias (penis deformity) in boys. <63 95% confidence interval 0, second-generation antihistamines a. drugs during the first trimester of pregnancy have been published, and. Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. 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