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Bartolomeis, Antipsychotics with different D2 dopamine receptor potency affect. and a moderate affinity, un-competitive, voltage- dependent NMDA receptor. What are the implications of D2 partial agonism? Aripiprazole binds to the D2 receptor with the same affinity than dopamine, but has a lower. D2 Family; D2, D3, D4 receptors; High correlation with antipsychotic activity; D4 is. from extrapyramidal pathways; Atypical antipsychotics have high D4 affinity. 79. Aripiprazole little or no EPS, less weight gain, or Q-T changes Akathesia. allegra azus Le proprietà di parziale agonista D2 dell'aripiprazolo contribuiscono a stabilizzare più che. Aripiprazole, a novel Antipsychotic, is a high-affinity partial agonist. modello di polidipsia indotta dagli agonisti quinpirolo e pramipexolo. (2002). Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at. new/4808-1-5189.php Although aripiprazole has only been, aripiprazole 10 or 15 mg once daily is. 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