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Vilazodone. This eMedTV Web article outlines the other drugs that can react with Viibryd and describes the. Trazodone. Depression Home > Viibryd Drug Interactions. posted in Viibryd (vilazodone HCl): I just learned about the new antidepressant. Trazodone is essentially a milder version of nefazodone. vermox allattamento Applies to: Adderall XR Viibryd (vilazodone). Viibryd has a serious potential to react with trazodone. J Clin Psychopharmacol. 1994 Jun;14(3):170-9. Comparison of bupropion and trazodone for the treatment of major depression. Weisler RH(1), Johnston JA. new/963-10-3239.php The name is vilazodone, which at once made me think of trazodone (Desyrel) and nefazodone (Serzone), antidepessants. 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