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( ICH ) occurs less frequently with NOACs compared with Warfarin ( Coumadin ). non-vitamin K antagonist oral anticoagulants during the period 2011-2014. new/8469-10-4827.php with or without symptomatic DVT. Enoxaparin 1 bid warfarin. Obs. period. Double-dummy period. 72 h. 6 months. End of treatment. No (i.e. non-valvular AF). Yes. Warfarin. No. of events 1. Connolly SJ, et al. N Engl J Med. 2009. over the period October 19, 2010 to. 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