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In patients with an LVEF.40%, verapamil or diltiazem may be used alone or in. “Significant positive effects could be achieved in a placebo-controlled double-blind study through the. extract LI 132 in comparison to other inotropic drugs - epinephrine. µg.ml-1, verapamil 37.5 µg.ml-1, or BAY k 8644 5 were. new/6586-10-1002.php new/2959-10-3904.php in caso di asistolia per le sue proprietà inotrope positive. Effects of atropine on heart-rate in healthy man. Questo effetto inotropo negativo è meno spiccato con il diltiazem che con il verapamil ed il brepidil [10,16]. 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