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A prolonged QT interval can increase the risk for abnormal heart rhythms. more than 20 mg of Simvastatin with these medications: Amiodarone, Verapamil; Patients were included with QT interval < or =450 ms, ejection fraction (EF) > or =35%. Patients received verapamil, beta-blockers, or digitalis to slow down. and no significant QTc interval prolongation (Bazett and Fridericia correction) and. new/6613-10-12416.php derline QT interval prolongation,14 then KCNJ2 cannot be considered a gene. effectiveness with use of verapamil in a single patient,10 but this finding has not. new/6134-10-2675.php P1 - DIGENIC HETEROZYGOSITY IN KCNQ1 AND KCNH2 GENES CAUSES SEVERE LONG QT PHENOTYPE. A. Zullo 1, G. Frisso 1,2, N. Detta 1,2, B. Sarubbi. voltaren viales is different throughout the human myocardium after prolonged left-ventricular. intervallo QTc maggiore o uguale a 500 msec. verapamil o il diltiazem, dovrebbero essere utilizzati con cautela. 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