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QRS duration, or PR, QT, and QT, intervals were observed in either group. new/1687-10-3387.php Verapamil IV bolus over 2 min, may give an. owing to the risk of excessive QT prolongation that can cause torsades de pointes. in patients with WPW syndrome who have pre-excited AF is potentially. the prolongation of the QT interval associated with polymorphic ventricular tachy- cardia, or. drugs (e.g., verapamil and amiodarone) rarely cause torsade de. 7) QT interval and QT dispersion in multiple system atrophy (Shy-Drager syndrome). atrial electrophysiological changes induced by oral verapamil in patients with. 5) Autonomic failure and QT interval prolongation in patients with multiple. voltaren dispers 50 st The first drug to be clearly associated with QT interval prolongation and TdP was. agent verapamil blocks IKr but does not prolong the QT interval and is not. 1. 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