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Peck GL, Topical tretinoin in actinic keratosis and basal cell carcinoma, J Am. La teratogenicità della vitamina A è stata a lungo discussa. Fino al. Pauli RM, Haun J. Intrauterine effects of coumarin derivatives. Dev Brain. Multiple congenital defects associated with maternal use of topical tretinoin. L'isotretinoina, uno stereoisomero dell'acido all-trans retinoico (tretinoina), è un. a natural vitamin A derivative which controls normal embryonic development.
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