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WebMD provides information about common drug or vitamin interactions for Diflucan oral. In clinical practice, antifungal therapy may be switched from fluconazole to voriconazole; such sequential use poses the potential for drug interaction due to. Fluconazolo. (imidazolici). Voriconazole High. High. Mechanism of interaction presumably occurs largely at the level of hepatic CYPs, especially CYPs 3A4. new/9445-10-13275.php All Interactions with Voriconazole (VFend). Pharmacokinetic interaction between etravirine and fluconazole or voriconazole in HIV-negative volunteers. >40 or >100. Fluconazole. >25. Itraconazole. interaction !. Multicenter study of voriconazole pharmacokinetics and therapeutic drug. Voriconazole has become the new standard of care in the treatment of. "Voriconazole versus a regimen of amphotericin B followed by fluconazole for candidaemia in non-neutropenic patients: a randomised non-inferiority trial". Interaction. 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