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Drug interaction Vardenafil may also interact with the following medications:. medicines for fungal infections (fluconazole, itraconazole, ketoconazole, voriconazole). mechanism drug interaction fluconazole amiodarone fluconazole ship uk diflucan kill work. triazole fluconazole voriconazole sertaconazole FLUCONAZOLO O ECHINOCANDINE ?. Safety profile. • Less drug-drug interactions than caspofungin. Caspofungin. Fluconazole. CI. AI. Voriconazole. BI. Cochrane Database Syst Rev. 2014 Feb 24;2:CD004707. doi: Voriconazole versus amphotericin B or fluconazole in. 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