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Use of perioperative beta-blockers in appropriate patients to prevent. Patient self-management for warfarin (Coumadin™) to achieve. Patients on oral anticoagulant therapy with warfarin and in need of oral surgery. The findings from this study suggest that a comprehensive perioperative. Perioperative Assessment and Management of the Surgical Patient with Neurologic Problems. Perioperative Evaluation of Patients with Hematologic Disorders. Does perioperative myocardial ischemia lead to postoperative myocardial infarction?. Hirsh J. Reversal of the anticoagulant effects of warfarin by vitamin K1. Many of these drugs interact with warfarin, but INR levels allows dose adjustment, which mitigates the risk of. Perioperative management. • Patients presenting. 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