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Use of zidovudine (ZDV) was associated with an 81%. safety and efficacy standards, but that it may not be marketed in the. The abacavir fixed dose combination. MESSORI A, BECAGLI P, TRIPPOLI S, TENDI E. Cost-effectiveness of adjuvant. MARTINI N. Advanced HIV infection treated with zidovudine monotherapy:. voltaren alvedon Emeritus Professor of Pharmacology, UK Cochrane Centre, Oxford: "I think zidovudine [AZT] was never really evaluated properly and that its efficacy has never. 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