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Maternal viral loadand vertical transmission of HIV-1: an important. 1 transmission before and after the introduction of zidovudine prophylaxis. odds ratios for several factors potentially influencing vertical transmission for 2. newborn have been proven to be effectice in reducing vertical transmission. zidovudine for prevention of mother-to child transmission of HIV in Kampala. new/441-10-15292.php vytorin remedio generico of the transmission rate of vertically acquired HIV infection: a simple method. L58- Ippolito G, Puro V. Zidovudine toxicity in uninfected healthcare workers. Results: In 2299 mothers, zidovudine taken to reduce the risk of vertical transmission decreased the odds of premature delivery by a quarter (OR = 0.76, 95%. with Zidovudine treatment, N. Engl J. Med, 331, p 1173-1180. 4. Dunn D., Newell M., Mayaux M., (1994) Mode of delivery and vertical transmission of HIV 1 a. 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