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Rationale for Multi-Target Drugs in Psychiatry; Drug molecules and biology:. of the anti-psychotic drug, Ziprasidone; The Rational Design of Triple Reuptake. ing director of the Division of Psychiatry in the Department of Molecular Medicine. PRACTICAL GUIDANCE FOR PRESCRIBING ZIPRASIDONE IN ACUTE. Published in International Journal of Molecular Sciences; 2015, Vol. Successful Ziprasidone Monotherapy in a Case of Delusional Parasitosis: A One-Year. Ziprasidone is a new generation antipsychotic that presents some possible differences compared to other antipsychotics, thus it is an antagonist of serotonin. 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