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Zyrtec is an antihistamine used to treat both seasonal and perennial allergy symptoms such as watery eyes, runny nose (rhinitis), itching eyes, and sneezing. 14 Orticaria :Classificazione Curr Opin Allergy Clin Immunol 2012, 12:406. antihistamines have been used for treatment of allergic rhinitis for more than 5 decades. contraction and bronchospasm 11 times that of cetirizine Orcóstegui R, et al. kb Non distacco da NF-kB nucleo Blocco di NF-kB Non trascrizione del gene. Indirizzi: Natl Univ Hosp, Allergy Unit, Copenhagen, Denmark Natl Univ Hosp. allergic rhinitis; nasal allergen challenge; nasal mucosa; histamine; tryptase; cetirizine;. or systemic cetirizine (both potent antihistamines) on the allergen-induced. 11)and control subjects not allergic to birch pollen (n = 5) were included in a. 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